The Gunners top the table with 67 points from 29 games, seven ahead of City on 60. A victory would take them to 70 points ahead of the international break, while Everton sit eighth with a strong away record including wins at Manchester United and Aston Villa.
Mikel Arteta's side carries momentum but faces fatigue concerns, with Martin Ødegaard doubtful due to knee trouble and Jarrad Branthwaite's fitness key for the visitors. Kickoff is at 5:30pm GMT in a match full of title-race stakes.
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