Villa are away to Lille in the first leg of their last-16 tie, while Forest will host FC Midtjylland.
Here, Sports Mole provides predictions for Thursday's Europa League fixtures.
In what will be the inaugural meeting between the two sides, Stuttgart welcome Porto to the MHPArena on Thursday for the first leg of their Europa League round-of-16 tie.
Die Roten secured a 4-2 aggregate victory over Celtic in the playoffs, while the Portuguese visitors gained direct passage to this stage after finishing inside the top eight of the league-phase standings