Eta steps up immediately until June following the sacking of Steffen Baumgart, with Union sitting 11th on 32 points from 29 games amid a string of poor results.
A former German youth international and Union's first female assistant coach, she previously led the club's U19 boys and managed a Bundesliga men's game last year.
Club sources praise her as a sharp tactician, and her first match is April 18 at home against Wolfsburg, where fans hope Union's gritty spirit shines through.
Historical decision by Union Berlin as German club appoint Marie-Louise Eta as their head coach until June.
Union lost at Heidenheim, sacked the head coach Steffen Baumgart and put Marie-Louise Eta in charge until the end of the season.
Ets becomes the first female head coach in the history of men’s Bundesliga.
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